Respiratory depression in tricyclic overdose.
نویسندگان
چکیده
منابع مشابه
Tricyclic antidepressant overdose: a review.
Overdoses of tricyclic antidepressants are among the commonest causes of drug poisoning seen in accident and emergency departments. This review discusses the pharmacokinetics, clinical presentation and treatment of tricyclic overdose.
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Prognostic factors for severe complications in tricyclic antidepressant (TCA) overdose remain unclear. We therefore evaluated the value of clinical characteristics and electrocardiograph (ECG) parameters to predict serious events (seizures, arrhythmia, death) in severe TCA overdose of 100 patients using logistic regression models for risk assessment. The overall fatality rate was 6%, arrhythmia...
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Tricyclic antidepressant (TCA) overdose necessitating intensive care unit (ICU) admission remains a significant problem in the Western Cape. In this retrospective study, we reviewed the course of life-threatening TCA overdose in our centre to identify potential prognostic indicators. TCA levels >1000 ng/ml were associated with QT and QRS prolongation and convulsions. However, no single paramete...
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Background. Psychiatric consultation is necessary for all patients with intentional poisoning and its reliability depends on the proper function of patients' memory performance. This study aimed to determine the possible memory impairment following acute TCAs' poisoning. Materials and Methods. In this cross-sectional study, patients with acute TCAs poisoning were allocated to two groups of seve...
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A 33-year-old female presented to the acccident and emergency (A&E) department having taken an overdose of Amitryptiline 3 h previously. On admission, she had a decreased level of consciousness and soon after arrival, she had a grand mal convulsion. She remained cardiovascularly stable with sinus rhythm on ECG. General examination revealed blisters and erythematous lesions on her left hand (Fig...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5800.631-b